This indicates an attack attempt to exploit a Memory Corruption vulnerability in Microsoft Office.
The vulnerability is due to an error when the vulnerable software handles a maliciously crafted Excel file. A remote attacker may be able to exploit this to execute arbitrary code within the context of the application, via a crafted Excel file.
Microsoft Excel 2003 Service Pack 3
Microsoft Office 2008 for Mac
System Compromise: Remote attackers can gain control of vulnerable systems.
Apply the most recent upgrade or patch from the vendor.