This indicates an attack attempt to exploit a Remote Command Injection vulnerability in Trend Micro Threat Discovery Appliance.
The vulnerability is due to improper validation of HTTP request parameters by the application. A remote attacker may be able to exploit this to execute arbitrary command within the context of the process, via a crafted HTTP request.
Trend Micro Threat Discovery Appliance versions 2.6.1062r1 and prior
System Compromise: Remote attackers can execute arbitrary command execution under the security context of the root user.
We currently are unaware of any vendor supplied patches for this issue.