This indicates an attack attempt to exploit a Memory Corruption vulnerability in G DATA Total Security.
The vulnerability is located in the "GDASpam.dll" ActiveX control through mis-use of "IsBlackListed" function. It may allow remote attackers to execute arbitrary code in the context of the application using the affected ActiveX control. Failed exploit attempts will likely cause the program to crash, resulting in a denial of service condition.
G Data Total Security 18.104.22.168
System Compromise: Remote attackers can gain control of vulnerable systems.
Apply the most recent upgrade or patch from the vendor.