This indicates an attack attempt to exploit a Memory Corruption vulnerability in Microsoft Office.
The vulnerability is due to an error when the vulnerable software handles a maliciously crafted Excel file. A remote attacker may be able to exploit this to execute arbitrary code within the context of the application, via a crafted Excel file.
Microsoft Excel 2007 Service Pack 3
Microsoft Excel 2010 Service Pack 2 (32-bit editions)
Microsoft Excel 2010 Service Pack 2 (64-bit editions)
Microsoft Excel 2013 Service Pack 1 (32-bit editions)
Microsoft Excel 2013 Service Pack 1 (64-bit editions)
Microsoft Excel 2013 RT Service Pack 1
Microsoft Excel 2016 (32-bit edition)
Microsoft Excel 2016 (64-bit edition)
Microsoft Excel for Mac 2016
Microsoft Office Compatibility Pack Service Pack 3
Microsoft Excel Viewer
System Compromise: Remote attackers can gain control of vulnerable systems.
Apply the most recent upgrade or patch from the vendor.